Human research · RCT
Acton JP et al., European Journal of Applied Physiology 2026
In healthy recreationally active men, 6 weeks of ubiquinol (300 mg/day) did not improve severe-intensity exercise time to exhaustion (primary outcome) vs placebo; muscle-biopsy subsample showed lower leak respiration, suggesting better mitochondrial coupling efficiency (surrogate).
Source: Effect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males. Acton JP, Alsharif NS, Bond JW, et al. European Journal of Applied Physiology. 2026;126(9):4763-4778. doi:10.1007/s00421-026-06275-w
Verified research card EL-20261017-03
